Table 1 Histological score
Score | Features |
|---|---|
0 | No lesions |
1 | Articular cartilage with variable GAG loss and/or chondrocyte hypertrophy and/or chondrocyte proliferation. Capsule is normal. No inflammation. |
2 | Articular cartilage with diffuse GAG loss +/- necrosis up to the tidemark; possible fibrillation or superficial erosion. Capsule is normal. No inflammation. |
3 | Articular cartilage with diffuse necrosis up to the tide mark + focal up to subchondral bone with bone remodeling. Capsule can be thickened with GAG deposition. |
4 | Articular cartilage with diffuse necrosis up to subchondral bone of at least one cartilage with diffuse bone remodeling. Capsule can be thickened with GAG deposition/osteophytes. |
5 | Complete loss/destruction of at least one articular cartilage, covered by fibrovascular tissue, entrapping also degenerated meniscus. Capsule can be thickened with GAG deposition/osteophytes. |