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  1. To explore the feasibility and clinical significance of computer-aided design 3D-printed percutaneous guides in femoral head necrosis drilling and decompression surgery, and compare it with traditional surgery...

    Authors: Shengtao Li, Jie Wang and Qiang Zhang
    Citation: BMC Musculoskeletal Disorders 2025 26:354
  2. The rise in the adoption of outpatient arthroplasty has been attributed to its cost-effectiveness, although safety concerns persist. In this meta-analysis, we compare inpatient and outpatient joint arthroplast...

    Authors: Nikhil Ponugoti and Henry Magill
    Citation: BMC Musculoskeletal Disorders 2025 26:349
  3. This retrospective case series evaluated mortality outcomes in patients with Vancouver B1 periprosthetic fractures (PPFs) managed non-operatively using a matched cohort approach. We hypothesize that mortality ...

    Authors: Mitchell Crebert, Michael Le, Geoff Murphy, Annamaria Frangos Young, Robert Molnar, Daniel Franks, Michael Symes and Maurice Guzman
    Citation: BMC Musculoskeletal Disorders 2025 26:348
  4. The purpose of this study was to retrospectively assess the clinical and radiographic outcomes of unilateral biportal endoscopic discectomy (UBED) in treating patients with single-level lumbar disc herniation ...

    Authors: Haozhong Wang, Changming Xiao, Kaiquan Zhang, Mingzhong Xie and Haoping Dai
    Citation: BMC Musculoskeletal Disorders 2025 26:347
  5. Carpal tunnel syndrome (CTS) is the most common peripheral nerve compression neuropathy. While established surgical techniques have demonstrated reliable outcomes and safety profiles, innovations in minimally ...

    Authors: Hsuan-Fu Chen, Shun-Min Chang, Chih-Ming Kao, Yu-Lin Chen, Li-Ting Kao, Ya-Chuan Hsu, Yin-Chih Fu, Yan-Hsiung Wang, Wen-Chih Liu and Tien-Ching Lee
    Citation: BMC Musculoskeletal Disorders 2025 26:346
  6. Knee pain is often an early sign of knee osteoarthritis (KOA). Physical activities (PA) constitute the recommended regime to those affected. However, knee-loading PA at work is linked to an increased risk for ...

    Authors: Margareta Törnblom, Emma Haglund, Ann Bremander, Anna Nilsdotter, Maria LE Andersson, Pasan Hettiarachchi, Peter J Johansson, Magnus Svartengren and Katarina Aili
    Citation: BMC Musculoskeletal Disorders 2025 26:345
  7. This study aims to assess the predictive value of preoperative parameters on recovery outcomes in patients with myelopathy caused by cervical ossification of the posterior longitudinal ligament (COPLL) undergo...

    Authors: Hao Yuan, Wei Lei, Wenping Li, Yunlong Zhou, Xufeng Jia, Daxiong Feng and Fei Lei
    Citation: BMC Musculoskeletal Disorders 2025 26:341
  8. Although intramedullary nailing has been established as the gold standard for treating femoral shaft fractures, nonunion following intramedullary nailing remains a major concern for clinicians, severely affect...

    Authors: Zhi Zhang, Xiong Wang, Qirong Zhou, Xingwen Xu, Jin Cui, Wenqiang Wei and Liehu Cao
    Citation: BMC Musculoskeletal Disorders 2025 26:340
  9. In this systematic review and meta-analysis, we evaluated and compared the efficacy and safety of platelet-rich plasma injection into corticosteroid injection in the treatment of tendinopathy.

    Authors: Zifeng Ye, Yiwei Yuan, Gaoyan Kuang, Liguo Qiu, Xuyi Tan, Zhi Wen and Min Lu
    Citation: BMC Musculoskeletal Disorders 2025 26:339
  10. General scapular exercises have been included in traditional postoperative rehabilitation for rotator cuff tears, but patients with concomitant scapular dyskinesia do not have identical scapular muscle imbalan...

    Authors: Jian-ning Sun, Qun-ya Zheng, Rui-song Wang, Yun-ru Ma and Peng Chen
    Citation: BMC Musculoskeletal Disorders 2025 26:338
  11. The lateral femoral wall is an important anatomical parameter of the proximal femur, but intramedullary nail fixation for intertrochanteric fractures may cause iatrogenic lateral wall fractures due to populati...

    Authors: Tianhao Shi, Xiaoyang Jia, Kun Zhang, Gengxin Jia, Zhenqi Yang, Minfei Qiang and Yanxi Chen
    Citation: BMC Musculoskeletal Disorders 2025 26:337
  12. In recent years, with the gaining popularity and wide application of total hip arthroplasty (THA), the incidence rate of periprosthetic femoral fractures (PFF) has increased. The treatment of PFF is difficult ...

    Authors: Jie Tang, Ying Hu, Ye Li, Shenghao Zhao and Yong Hu
    Citation: BMC Musculoskeletal Disorders 2025 26:336
  13. To diagnose cervical radiculopathy according to the International Association for the Study of Pain definition, signs of neurological deficits must be examined with the neurological examination. However, the d...

    Authors: Marzia Stella Yousif, Giuseppe Occhipinti, Filippo Bianchini, Daniel Feller, Annina B. Schmid and Firas Mourad
    Citation: BMC Musculoskeletal Disorders 2025 26:334
  14. Osteoarthritis (OA) is a joint disease closely associated with synovial tissue inflammation, with the severity of synovitis impacting disease progression. m7G RNA methylation is critical in RNA processing, met...

    Authors: Zhenhui Huo, Chongyi Fan, Kehan Li, Chenyue Xu, Yingzhen Niu and Fei Wang
    Citation: BMC Musculoskeletal Disorders 2025 26:333
  15. Physiotherapy is recommended for people with hemophilic arthropathy (PwHA) to improve musculoskeletal health and is typically administered in 2 or 3 sessions per week. We aimed to investigate the effects of on...

    Authors: Ayse Merve Tat, Necati Muhammed Tat, Serbay Sekeroz, Meryem Buke and Kamuran Karaman
    Citation: BMC Musculoskeletal Disorders 2025 26:332
  16. The role of nuclear translocation in osteoarthritis (OA) pathogenesis has garnered increasing attention in recent years. Extensive research has demonstrated that FHL2 acts as a nuclear transmitter through inte...

    Authors: Yicheng Li, Fei Wang, Baochao Ji, Abdusami Amati and Li Cao
    Citation: BMC Musculoskeletal Disorders 2025 26:331
  17. Claims data are often used to investigate the quality of care for patients with low back pain (LBP). However, there is no standard regarding the preferred choice of ICD-10 codes for identifying patients with L...

    Authors: Elisa Kasbohm, Jean-François Chenot, Carsten Oliver Schmidt and Julia Truthmann
    Citation: BMC Musculoskeletal Disorders 2025 26:330
  18. Due to the high stresses placed on the upper cervical spinal region, achieving firm fixation and solid bony fusion is essential for good surgical outcomes. However, few reports have addressed bony fusion in pr...

    Authors: Masashi Uehara, Shota Ikegami, Hiroki Oba, Terue Hatakenaka, Daisuke Kurogochi, Takuma Fukuzawa, Shinji Sasao, Tetsuhiko Mimura and Jun Takahashi
    Citation: BMC Musculoskeletal Disorders 2025 26:328
  19. Vertebral height loss of fractured vertebrae treated by percutaneous vertebral augmentation (PVA) for osteoporotic vertebral compression fracture (OVCFs) during follow-up had been reported. Mostly, vertebral h...

    Authors: Benqiang Tang, Xueming Chen, Libin Cui, Yanhui Wang, Xin Yuan, Yadong Liu and Liang Liu
    Citation: BMC Musculoskeletal Disorders 2025 26:327
  20. Musculoskeletal disorders (MSDs) and injuries are among the leading causes of physical disability and chronic pain worldwide, imposing a significant burden on healthcare systems and economies. Effective manage...

    Authors: Alireza Banaye Yazdipour, Seyed Mohammad Ayyoubzadeh, Salman Nazary-Moghadam, Leila Shahmoradi and Khalil Kimiafar
    Citation: BMC Musculoskeletal Disorders 2025 26:326
  21. To investigate the correlation between abdominal adipose tissue (AAT), psoas muscle fat content, and lumbar vertebral bone mineral density (BMD) in different age and sex groups using quantitative CT(QCT) imaging.

    Authors: Hua Xu, Zhi Wang, Xiang-hong Meng, Feng-ling Zhu and Yu-qiao Zhong
    Citation: BMC Musculoskeletal Disorders 2025 26:325
  22. Due to its occult position, complex anatomical structure, and spatial relationships, the causative tumor of Tumor-Induced Osteomalacia (TIO) in the hip region is quite difficult to detect and qualitatively dia...

    Authors: Shuzhong Liu, Xi Zhou, Jinyi Xing, Annan Liang, Yong Liu and Weibo Xia
    Citation: BMC Musculoskeletal Disorders 2025 26:324
  23. Primary malignant tumors of the proximal femur in children are rare, and there is no consensus about the optimal reconstruction method for this condition. While methods for biological reconstruction—such as va...

    Authors: Khodamorad Jamshidi, Abolfazl Bagherifard, Seyyed Saeed Khabiri and Alireza Mirzaei
    Citation: BMC Musculoskeletal Disorders 2025 26:323
  24. Although percutaneous kyphoplasty (PKP) is used to treat severe osteoporotic vertebral compression fractures (OVCF), the unsatisfactory effect of bone cement reduction and leakage is a concern. In recent years...

    Authors: Peng Liu, Jiang Hu, Wei Zhang, Fei Wang, Liuyi Tang, Weijun Zhou and Shu Lin
    Citation: BMC Musculoskeletal Disorders 2025 26:322
  25. Intraarticular (e.g., Hoffa-type) fractures are usually stabilized with titanium screws, which may necessitate later implant removal. The aim of this study was to compare the biomechanical strength and stabili...

    Authors: Larissa Felten, Filippo Migliorini, Frank Hildebrand and Christian David Weber
    Citation: BMC Musculoskeletal Disorders 2025 26:321
  26. Minimally Invasive Plate Osteosynthesis (MIPO) has emerged as an option for the treatment of fractures; however, there is limited literature regarding its application in radius shaft fractures. The purpose of ...

    Authors: Hyun-Tak Kang, Yang-Hoon Jo and Hong-Je Kang
    Citation: BMC Musculoskeletal Disorders 2025 26:320
  27. Osteomyelitis involves bone destruction, impaired bone formation, and systemic inflammation. Dexmedetomidine (DXMT) possesses antioxidant, anti-inflammatory, and anti-apoptotic properties alongside sedative an...

    Authors: Merve Hayriye Kocaoğlu, Günseli Çubukçuoğlu Deniz, Duru Aras-Tosun, Evrim Güneş Altuntaş and Erkan Tuncay
    Citation: BMC Musculoskeletal Disorders 2025 26:319
  28. The aging population is experiencing a rising incidence of musculoskeletal problems and degenerative spinal deformities. Adult spinal deformity (ASD) presents challenges, with associated risks in open surgery....

    Authors: Chun Yeh, Pang-Hsuan Hsiao, Michael Jian-Wen Chen, Yuan-Shun Lo, Chun Tseng, Chia-Yu Lin, Ling-Yi Li, Chien-Ying Lai, Chien-Chun Chang and Hsien-Te Chen
    Citation: BMC Musculoskeletal Disorders 2025 26:318
  29. Previous research has demonstrated impaired proprioception and poorer responses to tactile deep pressure, visual-tactile integration, and vestibular stimuli in individuals with generalized hypermobility, poten...

    Authors: Ivana Hanzlíková, Aneta Ruská, Kristýna Jančíková and Kim Hébert-Losier
    Citation: BMC Musculoskeletal Disorders 2025 26:317
  30. In recent years, an increase in surgeries to treat clavicle injuries has been reported. It has been hypothesized that the studies regarding the beneficial effect of surgery in patients with displaced clavicle ...

    Authors: Catalina Vidal, Rodrigo de Marinis, Rodrigo Liendo, Isadora Silva, María Jesús Lira and Julio J Contreras
    Citation: BMC Musculoskeletal Disorders 2025 26:316
  31. Knee osteoarthritis (KOA) is a chronic, disabling condition without a definitive cure, and current management strategies prioritize symptom relief and slowing disease progression rather than addressing the und...

    Authors: Anas Dekhissi, Fatima Zahrae Taik, Fatima Zahra Aharrane, Anass Adnine, Nihad Takhrifa, Maryam Fourtassi and Fatima Ezzahra Abourazzak
    Citation: BMC Musculoskeletal Disorders 2025 26:315
  32. Gas-containing lumbar disc cysts (LDCs) are a rare spinal pathology that frequently manifest as sciatica and exhibit clinical features akin to those observed in lumbar disc herniation. Their radiological prese...

    Authors: Guijun Zhang, Lei Ren, En Song and Shengjun Shen
    Citation: BMC Musculoskeletal Disorders 2025 26:314
  33. Knee osteoarthritis (OA) is a debilitating condition that manifests as knee pain and dysfunction. Clinicians prefer non-surgical options such as intra-articular injections for mild to moderate disease. Dextros...

    Authors: Alireza Teymouri, Nafiseh Birang, Maryamsadat Fakheri and Aref Nasiri
    Citation: BMC Musculoskeletal Disorders 2025 26:313
  34. To characterize the association between metformin use and risk of total joint replacement in patients with diabetes using data from Alberta’s Tomorrow Project (ATP), a population-based cohort study of chronic ...

    Authors: Ming Ye, Jennifer E. Vena, Grace Shen-Tu, Jeffrey A. Johnson and Dean T. Eurich
    Citation: BMC Musculoskeletal Disorders 2025 26:312
  35. The burden of osteoarthritis (OA) in multiple joints is high. For patients with bilateral knee OA there is no clear recommendation when to time the second surgery. The purpose of this study was therefore to co...

    Authors: Anne Elisabeth Postler, Paula Krull, Yinan Wu, Klaus-Peter Günther, Oliver Melsheimer, Arnd Steinbrück and Jörg Lützner
    Citation: BMC Musculoskeletal Disorders 2025 26:311
  36. There exists a paucity of data on the relationship between psychological factors and return to sport in patients who undergo surgery for complex patellofemoral instability (PFI). The purpose of this study was ...

    Authors: Maximilian Hinz, Peter Rab, Moritz Brunner, Marco-Christopher Rupp, Armin Runer, Luca Grüning, Lisa Rahn, Sebastian Siebenlist and Andrea Achtnich
    Citation: BMC Musculoskeletal Disorders 2025 26:310
  37. Neutrophil extracellular trap (NET) has been implicated in cancer progression and metastasis. Nevertheless, the role of the NET-related gene, formyl peptide receptor 1 (FPR1), in osteosarcoma (OS) remains larg...

    Authors: Shihao Li, Qiong Yuan, Yuanyuan Zhang and Haiyang Zhang
    Citation: BMC Musculoskeletal Disorders 2025 26:309
  38. Dual-mobility cup (DMC) is gaining increasing attention in total hip arthroplasty (THA) revision due to its numerous advantages. However, the prognosis after isolated cup revision with DMC remains unclear. Thi...

    Authors: Tae Woo Kim, Min Uk Do, Kyeong Baek Kim, Jae Jin Kim, Kuen Tak Suh and Won Chul Shin
    Citation: BMC Musculoskeletal Disorders 2025 26:308
  39. Muscle hernia refers to the localized protrusion of muscle from a weak point due to fascia defects. Muscle hernias can be classified as structural or traumatic. There are many reasons for the formation of fasc...

    Authors: Shihong Li, Zhiqiang Ma, Ruonian Zhai, Junlong Wu, Peng Zhou, Yingchao Tang, Qingyun Xie and Song Chen
    Citation: BMC Musculoskeletal Disorders 2025 26:307
  40. We aimed to investigate the influence of hydrorelease (HR) on the gliding resistance force between the aponeurotic fascia and epimysial fascia of tibialis anterior and between two epimysial fasciae of tibialis...

    Authors: Kousuke Shiwaku, Hidenori Otsubo, Daisuke Suzuki, Calmero Pirri, Taiki Kodesyo, Tomoaki Kamiya, Keigo Taniguchi, Hirofumi Ohnishi, Atsushi Teramoto and Carla Stecco
    Citation: BMC Musculoskeletal Disorders 2025 26:306
  41. Haemorrhagic cerebral infarction with cervical infection is a severe and complex complication in spinal surgery. This paper report a case of intracranial hematoma secondary to cerebrospinal fluid leakage after...

    Authors: Zhen-Shan Yuan, Lian-Song Lu and Yong Hu
    Citation: BMC Musculoskeletal Disorders 2025 26:305
  42. External fixators have been extensively applied in the treatment of open tibiofibular fractures and have yielded positive outcomes. The stability of an external fixator primarily hinges on its structure. Emplo...

    Authors: Xubiao Ye, Jinling Luo, Pu Chen, Xiaohua Wei and Shifeng Liu
    Citation: BMC Musculoskeletal Disorders 2025 26:304
  43. Low back pain developers (PDs) are individuals at a high risk of developing low back pain (LBP), especially during prolonged standing. Understanding their characteristics is essential for devising effective pr...

    Authors: Saeedeh Abbasi, Hooman Minoonejad, Hamed Abbasi and Seyed Hamed Mousavi
    Citation: BMC Musculoskeletal Disorders 2025 26:299

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