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  1. Estimated glucose disposal rate (eGDR) is a novel insulin resistance (IR) assessment surrogate. Although it has shown promising potential in other metabolic disease studies, no research has yet explored its re...

    Authors: Zhiqiang Que, Dingqiang Chen, Huirong Cai, Weibin Lan, Yuxuan Huang and Gang Rui
    Citation: BMC Musculoskeletal Disorders 2025 26:302
  2. With the gradual promotion of minimally invasive plate osteosynthesis (MIPO) in the treatment of proximal humeral fractures, some patients using the proximal humeral internal locking system (PHILOS) plate expe...

    Authors: Jiadi Le, Jianpeng Lu, Jianxiong Zhang, Zhenghao Wu and Long Chen
    Citation: BMC Musculoskeletal Disorders 2025 26:301
  3. The link between serum insulin level and low muscle mass among older adults is not yet fully understood. This study seeks to investigate this association using data from a nationally representative large-scale...

    Authors: Guofang Sun, Jianjun Liang, Dechao Chen, Kongjun Zhao and Wangmi Liu
    Citation: BMC Musculoskeletal Disorders 2025 26:300
  4. The aim of this study was to assess the self-reported quality of care for people with knee osteoarthritis in Singapore and to investigate the associations between participant characteristics and functional out...

    Authors: Ren Hao Linus Tan, Anthony J. Goff, Chien Joo Lim and Yijia Bryan Tan
    Citation: BMC Musculoskeletal Disorders 2025 26:298
  5. To investigate the risk factors for radiographic adjacent segment disease (RASD), with a focus on the impact of screw position, following anterior cervical discectomy and fusion with plate fixation (ACDF-P).

    Authors: Feng Wang, Jiawei Lu, Bijun Wang, Ziqi Zhu, Beiduo Shen, Kai Guo, Zhaoyu Ba, Yufeng Huang and Desheng Wu
    Citation: BMC Musculoskeletal Disorders 2025 26:297
  6. This retrospective study aimed to evaluate the clinical efficacy and surgeon’s neck flexion time between unilateral biportal endoscopic lumbar fusion (UBE-LIF) versus minimally invasive transforaminal lumbar f...

    Authors: Wen-Bo Wei, Sha-Jie Dang, Da-Peng Duan, Wei Zhao and Ling Wei
    Citation: BMC Musculoskeletal Disorders 2025 26:296
  7. Proper muscle tension is an essential element for correct body posture and motion. It should be high enough to counteract gravity and low enough to provide smooth, selective movement and isolated activity. Imp...

    Authors: Mirosław Mrozkowiak, Marta Stępień-Słodkowska and Marek Sokołowski
    Citation: BMC Musculoskeletal Disorders 2025 26:295
  8. Osteoporosis is a global health concern that is likely to increase with a rapidly ageing world population. It affects one in three women and one in five men over the age of 50. Although there is a large body o...

    Authors: Francine Toye, Karen Louise Barker, Sarah Drew, Tanzeela Y. Khalid and Emma M. Clark
    Citation: BMC Musculoskeletal Disorders 2025 26:294
  9. To investigate the clinical effect of vertebroplasty through unilateral upper edge of transverse process in the treatment of lumbar osteoporotic vertebral compression fracture (OVCF), and to explore the surgic...

    Authors: Junru Zheng, Haopeng Luan, Ying He, Lei Hong, Pengyuan Han, Xiaonan Wang, Xing Wang, Qiaojuan Wang and Qisong Shang
    Citation: BMC Musculoskeletal Disorders 2025 26:293
  10. In situations of osteoarthritis (OA), the therapeutic value of knee arthroscopy is still a topic of discussion that is ongoing. This study aims to produce data about the relevance of arthroscopy and total knee...

    Authors: Sang Hyun Samuel Kang, Annie Yunser Hwang, David Ta-chun Ho, Thirumurugan Thangarajah, Lahann Wijenayake, Simon Parfit, Andrew Mclean and James Clayton
    Citation: BMC Musculoskeletal Disorders 2025 26:292
  11. Despite the association between osteoporosis treatment and reduced mortality, evidence on specific-cause mortality is lacking. Therefore, this study explored the association between osteoporosis under treatmen...

    Authors: Hyun Youk, Hee Young Lee, Eun Young Lee, Yoon Ji Kim, Ji Yeong Park, Hyo Geun Choi, Hyun Sik Kim and Jung Woo Lee
    Citation: BMC Musculoskeletal Disorders 2025 26:291
  12. Pulsed electromagnetic fields (PEMF) and stretching exercises are safe and noninvasive methods that could have a therapeutic effect on tissue healing. This study aimed to assess the effectiveness of these meth...

    Authors: Mesut Ergan, Tahir Keskіn, İbrahim Aydın Candan, Yalçın Erzurumlu, Halil Aşci, Selçuk Çömlekçı and Ferdi Başkurt
    Citation: BMC Musculoskeletal Disorders 2025 26:289
  13. Scapulohumeral periarthritis (SP) is a disease caused by chronic inflammation of the shoulder soft tissue area, which is characterized by shoulder pain and limited mobility. Due to the long course of disease, ...

    Authors: Chengyu Zhu, Xueyan Huang, Jiaying Yu, Ying Feng and Haifang Zhou
    Citation: BMC Musculoskeletal Disorders 2025 26:288
  14. Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) present similar symptoms in the early stage, complicating their differentiation. This study aims to develop a classification model using ra...

    Authors: Taiya Chen, Haoran Zhu, Yingyi Hu, Yang Huang, Wengan He, Yizhen Luo, Zeqi Wu, Diangang Fang, Longwei Sun, Hongwu Zeng and Zhiyong Li
    Citation: BMC Musculoskeletal Disorders 2025 26:287
  15. The transfer of mitochondria from stem cells effectively attenuates the viability of inflammatory cells. However, there is a paucity of research supporting the inhibitory effect of stem cells on inflammatory b...

    Authors: Xingfu Li, Jingyue Su, Xiang Liu, Wei Lu and Zhenhan Deng
    Citation: BMC Musculoskeletal Disorders 2025 26:286
  16. Previous view is that femoral anteversion angle (FAA) is equivalent to femoral torsion (FT) and as an indication for derotational distal femoral osteotomy (DDFO) combined with medial patellofemoral ligament re...

    Authors: Zhengyi Ni, Kehan Li, Xiaobo Chen, Yitong Hu, Jingting Zhang and Fei Wang
    Citation: BMC Musculoskeletal Disorders 2025 26:284
  17. To explore incidence and predictive factors for distal pedicle screw loosening (DPSL) followed posterior corrective surgery for degenerative lumbar scoliosis (DLS).

    Authors: Hongru Yuan, Yilei Liu, Chenjie Dai, Puxin Yang, Yachong Huo, Di Zhang and Hui Wang
    Citation: BMC Musculoskeletal Disorders 2025 26:283
  18. Foot orthoses produced using computer-aided-design and manufacture (CAD/CAM) are commonly used to treat musculoskeletal conditions of the foot and ankle, however minimal evidence exists as to the most effectiv...

    Authors: Laura Barr, Jim Richards, Colette Dickson, Jillian Tawse, Nikki Munro, Hannah Scott, Aimie Holland and Graham J. Chapman
    Citation: BMC Musculoskeletal Disorders 2025 26:282
  19. Tenosynovial giant cell tumor (TGCT), previously referred to as pigmented villonodular synovitis (PVNS), is a rare, locally aggressive proliferative disorder of the synovium. It typically affects large joints,...

    Authors: Khalid AlHarbi and Sultan AlHussain
    Citation: BMC Musculoskeletal Disorders 2025 26:281
  20. Anatomical repair of Bankart lesions and restoring the tension of the antero-inferior capsulo-labral complex is the optimum method of surgical treatment with a variety of fixation methods including suture anch...

    Authors: Amr Samir Rashwan, Al-Qassem Amin, Sherif Hamdy Zawam, Alaa Mohy-Eldin Soliman and Mahmoud El-Desouky
    Citation: BMC Musculoskeletal Disorders 2025 26:280
  21. According to the mobilization technique of the intraoperative patella, total knee arthroplasty (TKA) can be categorized into patellar eversion (PE) and patellar lateral retraction (PLR). Comparisons between th...

    Authors: Mingjie Dong, Xiaoyu Sun, Hao Fan, Weiping Ren, Yushan Wang, Yingjie Gao, Pengfei Shao, Yu Gao, Qiang Jiao and Yi Feng
    Citation: BMC Musculoskeletal Disorders 2025 26:279
  22. Prader-Willi syndrome (PWS) is a rare disease. Hip dysplasia is an orthopedic-related disease of PWS. Limited literature exists on the prevalence, diagnosis, and surgical management of late diagnosed hip dyspl...

    Authors: Yueqiang Mo, Chunxing Wu, Peng Huang, Dahui Wang, Yanhui Jing and Bo Ning
    Citation: BMC Musculoskeletal Disorders 2025 26:278
  23. The purposes of the present study are to investigate the effects of reduced muscle loading by prolonged immobilization on the regeneration of fibrocartilaginous enthesis through endochondral ossification in ra...

    Authors: Xiaoke Shang, Can Chen, Jiefu Zhou, Yang Yang and Jin Qu
    Citation: BMC Musculoskeletal Disorders 2025 26:277
  24. An oligopeptide hepcidin is encoded by the human HAMP gene (Hamp in mice). Its deficiency can result in iron overload, while excess may lead to iron deficiency. Hepcidin knockout mice exhibited iron accumulati...

    Authors: Xin Chen, Jianping Wang, Chenxiao Zhen, Gejing Zhang, Zhouqi Yang, Youjia Xu and Peng Shang
    Citation: BMC Musculoskeletal Disorders 2025 26:276
  25. The purpose of this study was to evaluate whether the combination of preoperative planning software combined with arithmetic hip-knee-ankle angle (aHKA) can help patients who underwent uni-compartmental knee a...

    Authors: Changquan Liu, Cheng Huang, Xin Suyalatu, Qidong Zhang, Yiling Zhang, Wei Sun, Wanshou Guo and Weiguo Wang
    Citation: BMC Musculoskeletal Disorders 2025 26:275
  26. Osteoarthritis (OA) is closely related to aging, and autophagy is implicated in the retardation of aging. Activated synoviocytes play important roles in OA; the synoviocytes could produce osteopontin (OPN) and...

    Authors: Min Li, Chang-Bao Wei, Hai-Feng Li, Ke He, Rui-Jun Bai and Fang-Jie Zhang
    Citation: BMC Musculoskeletal Disorders 2025 26:274
  27. Adult spinal deformity (ASD) is a spectrum of abnormalities of the thoracic and lumbar spine and has an increasing prevalence. It is associated with significant physical and mental disability in symptomatic pa...

    Authors: Thomas Pieters, Gabrielle Santangelo, Taylor Furst and Daniel M. Sciubba
    Citation: BMC Musculoskeletal Disorders 2025 26:272
  28. Although movement representation techniques has originally been used in neurological rehabilitation, growing researches suggests that it may also introduce advantageous effects to individuals with orthopaedic ...

    Authors: Xin Yu, Hu-jun Wang, Xian-feng Guo, Qian Pei, Xiao-quan Wang, Wen-qian Zhi, Jie Hao, Jing-xuan Wang and Qiang Huang
    Citation: BMC Musculoskeletal Disorders 2025 26:271
  29. Double crush syndrome (DCS) is a relatively rare nerve compression syndrome among peripheral nerve compression diseases. However, ulnar nerve double entrapment caused by peri-cubital tunnel ganglion cysts has ...

    Authors: Gaoming Gong, Leining Wang, Jinhao Zhang, Zhihui Huang, Yulong Wang and Kunpeng Song
    Citation: BMC Musculoskeletal Disorders 2025 26:270
  30. Low back pain (LBP) is a long-lasting condition with a variable course rather than pain episodes of unrelated occurrences. Thus, the remission stage between the symptom recurrence is critical. This study aimed...

    Authors: Xiaomeng Xu, Yusuke Sekiguchi, Keita Honda and Shin-Ichi Izumi
    Citation: BMC Musculoskeletal Disorders 2025 26:269
  31. Osteoporosis (OP), a systemic bone disease, is characterized by degeneration of bone microstructure and susceptibility to fracture. Teriparatide (TPD) is an active fragment of human endogenous parathyroid horm...

    Authors: Jiaxin Fu, Zhi Liu, Guangxin Zhang and Chun Zhang
    Citation: BMC Musculoskeletal Disorders 2025 26:268
  32. OLIF (oblique lumbar interbody fusion) is a minimally invasive surgery to treat spinal instability. However, clinical studies indicated the early degeneration of adjacent segments after surgery. The rod stiffn...

    Authors: Po-Hsin Chou, Jing-Jie Chen, Chen-Sheng Chen, Shih-Tien Wang, Chien-Lin Liu and Shih-Liang Shih
    Citation: BMC Musculoskeletal Disorders 2025 26:267
  33. We aimed to systematically review and conduct a meta-analysis of the available evidence about the association between dietary acid load (DAL) and fractures in adults.

    Authors: Atieh Mirzababaei, Mojtaba Daneshvar, Vahid Basirat, Omid Asbaghi and Elnaz Daneshzad
    Citation: BMC Musculoskeletal Disorders 2025 26:266
  34. Musculoskeletal disorders (MSDs) are common work-related conditions that affect the musculoskeletal system owing to poor ergonomic practices, overexertion, and repetitive motions. Globally, MSDs account for a ...

    Authors: Ebrima Touray, Lamin Sambou, Balla Jammeh, Sambou L S Kinteh, Bakary Kinteh and Amadou Barrow
    Citation: BMC Musculoskeletal Disorders 2025 26:265
  35. The Charnley stem design has evolved, with notable modifications from the 6th generation (Elite Plus) to the 7th generation (C-stem), potentially affecting load transmission and clinical outcomes. This study a...

    Authors: Shota Nakagawa, Shuichi Miyamoto, Takushi Nakatani, Chiho Suzuki, Taisei Kawamoto, Yoshiyuki Shinada and Satoshi Iida
    Citation: BMC Musculoskeletal Disorders 2025 26:264
  36. Various conservative and non-conservative methods have been debated for their effectiveness in treating relapsed idiopathic congenital talipes equinovarus (CTEV). The aim of this work was the assessment of rep...

    Authors: Khalaf Fathy Elsayed Ahmed, Ashraf Rashad Marzouk and Marwan Shams Eldin
    Citation: BMC Musculoskeletal Disorders 2025 26:263
  37. The learning curve of total hip arthroplasty (THA) using the anterior approach in the supine position is considered to be long owing to limited surgical field visualization. This study aimed to investigate the...

    Authors: Tetsuya Tachibana, Hiroki Katagiri, Takahisa Ogawa, Gaku Koyano and Tetsuya Jinno
    Citation: BMC Musculoskeletal Disorders 2025 26:262
  38. To study the relationship between red blood cell distribution width (RDW) and short-term mortality of hip fracture in middle-aged and older adults.

    Authors: Xiao-feng Liu, Yong-qiang Zheng, Liang Lin, Zhen-yu Lin, Hong-peng Zhang, Xiao-peng Huang, Ze-feng Wang and Jin-shan Zhang
    Citation: BMC Musculoskeletal Disorders 2025 26:261
  39. C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are valuable markers for detecting periprosthetic joint infection (PJI) post-total knee arthroplasty (TKA). However, their prolonged elevation ...

    Authors: Mustafa Alper Incesoy, Cemil Burak Demirkiran, Hakan Batuhan Kaya, Muhammed Ali Geckalan, Aysegul Yabaci Tak, Nurzat Elmali, Fatih Yildiz and Gokcer Uzer
    Citation: BMC Musculoskeletal Disorders 2025 26:260
  40. Usually, comminuted fractures contain fragments that are too small for fixation with Kirschner (K)-wires or screws. For those bony or osteochondral fragments, a bone adhesive would be desirable to, for example...

    Authors: Philipp Heilig, Sina Ritzmann, Maximilian Heilig, Martin Cornelius Jordan, Rainer Heribert Meffert, Uwe Gbureck and Stefanie Hoelscher-Doht
    Citation: BMC Musculoskeletal Disorders 2025 26:258
  41. Instrument-assisted soft tissue mobilization (IASTM) is popular in the treatment of musculoskeletal disorders. However, the current literature has produced varying results. The purpose of this study was to col...

    Authors: Sien Tang, Li Sheng, Xiating Wei, Mingjie Liang, Jinming Xia and Jueru Chen
    Citation: BMC Musculoskeletal Disorders 2025 26:257
  42. The duration of a single fascia iliaca compartment block (FICB) with ropivacaine is limited. This study investigated whether methylene blue as an adjuvant anesthetic in FICB can enhance the postoperative analg...

    Authors: Yang Zhang, Shun Yang, Zi-Ru Lu, Feng Zhou and Mei-Yu Liu
    Citation: BMC Musculoskeletal Disorders 2025 26:256
  43. Excessive sliding of cephalic components of cephalomedullary nails has been established to be significantly associated with the development of mechanical failures and unfavorable results in the surgical treatm...

    Authors: Shian Zhang, Rui Wang, Jingqiao Li, Chengsi Li, Tianyu Wang, Yanjiang Yang, Haichuan Guo, Dongwei Wu and Yanbin Zhu
    Citation: BMC Musculoskeletal Disorders 2025 26:255
  44. Early exercise is a physical adjuvant therapy that begins on day 1 postoperatively. It prevents postoperative stiffness, fatty infiltration, muscle atrophy and loss of range of motion. Usually, use of a brace ...

    Authors: Boran Hao, Hongqiu Li and A. Liang
    Citation: BMC Musculoskeletal Disorders 2025 26:254
  45. Nonunion is a common complication following foot and ankle arthrodesis. This study endeavoured to determine the risk factors for nonunion in foot and ankle arthrodesis.

    Authors: Chen-Hao Chiang, Chang-Hao Lin, Hsin‑Yi Yang, Sheng-You Su, Yueh-Han Hsu, Chi-Ming Huang and Sheng-Pin Lo
    Citation: BMC Musculoskeletal Disorders 2025 26:253
  46. Bi-cruciate retaining (BCR) total knee arthroplasty (TKA) is considered to provide improved clinical function and kinematics compared with conventional TKA, but it is unclear which factors affect clinical outc...

    Authors: Shine Tone, Yohei Naito, Hiroki Wakabayashi, Akihiro Sudo and Masahiro Hasegawa
    Citation: BMC Musculoskeletal Disorders 2025 26:251

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